gamelook

What changed in The Binding of Isaac in 2025

5 updates · 2 main milestones · Sep 10, 2025 to Sep 11, 2025

  1. 4 events
    Mewgenics Gameplay Video Releasednew content

    First gameplay video of Mewgenics showcasing its features.

    Steam
    Mom's Knife Enhancementbalance change

    Mom's Knife can now do more stabbing, with a visual detail in the knife's reflection.

    Steam
    Ride the Duke of Flies in Fortnitenew contentMilestone

    Players can now ride the Duke of Flies as part of the crossover.

    Steam
    Fortnite Crossover with Isaacnew contentMilestone

    Isaac is now a Back Bling in Fortnite, featuring animations and interactions.

    Steam
  2. 1 event
    Conquest T-shirt and Promo Card Releasenew content

    The final shirt in the Horsemen series, Conquest, comes with a limited-edition alt-art promo card for Four Souls.

    Steam